Ibogaine Information

Universal Ibogaine

Ibogaine is a neuroactive compound which can be derived from various plants. Ibogaine has been shown to have a profound effect on the human brain. When administered in a clinical setting by trained facilitators and given the proper dosage, mindset and setting, ibogaine has demonstrated an ability to reset the brain and nervous system to pre addicted states.

Ibogaine appears to repair damaged brain tissues and its effects last long enough for a patient to begin to recover and rebuild their lives.

Please contact us to learn more.

Ibogaine is a powerful medicine which must be administered in a supervised medical setting following rigorous screening and validation.  The safety protocol developed at our research partner clinic has successfully aided over 3700 people with zero ibogaine fatalities.    

When administered in a clinical setting with professionals trained in our protocols, ibogaine can be a safe fast and relatively pain free method of opioid detox.  Ibogaine has also shown promise in the interruption of other addictions both substance and behavior related. 

We are working with appropriate regulators to demonstrate the safety and efficacy of the medicine and our treatment protocol.

Ibogaine is a naturally occurring psychoactive substance found in the root bark of the iboga plant.  Ibogaine can also be isolated from other plants. 

Ibogaine has been used in for centuries if not millennia in West Central Africa by both the Pygmy tribes and the Bwiti spiritual tradition.  

Ibogaine’s anti addictive properties were discovered in the 1960s and since then a large body of academic research has been conducted to validate its safety and efficacy.

History of Ibogaine

Some Major Milestones in Finding the Cure


Iboga root bark is used by forest dwelling Pygmy tribes and shared as sacrament with other cultures.

Discovered & Named

The first botanical description of the Tabernanthe iboga plant was made in 1889. Ibogaine was first isolated from T. iboga in 1901 by Dybowski and Landrin

Sold in France

1930 - 1960:
Ibogaine was sold in France in the form of Lambarène; the drug enjoyed some popularity among post-World War II athletes. Lambarène was withdrawn from the market in 1966 when the sale of ibogaine-containing products became illegal in France.

Howard Lotsof

At the age of 19, Lotsof was addicted to heroin and took an experimental dose of ibogaine. When he emerged from the experience he realized he had gone 48 hours without using heroin, had no withdrawal symptoms and no cravings. Howard dedicated the rest of his life to scientific research and medicalization of ibogaine.

Deborah Mash

The United States FDA grants Dr Mash an Investigational New Drug license to permit her to research the anti addictive properties of ibogaine. Dr Mash conducts extensive research and isolates the metabolite Noribogaine and commences clinical trials in the USA. Dr Mash trains a number of pupils including Dr Alberto Sola.

Dr. Alberto Sola

Under the direct supervision of Dr Deborah Mash, Dr. Sola opens the historic Clear Sky Recovery clinic in Cancun Mexico, a district where ibogaine is unregulated. Dr Sola perfects the treatment protocol and has treated over 3700 patients for addiction interruption using ibogaine hydrochloride. Dr Sola has administered more ibogaine treatments than anyone else in the world.

Universal Ibogaine

Dr Sola meets Canadian finance icon Shayne Nyquvest and Universal Ibogaine is born with the vision to bring the incredible healing power of ibogaine to the world through a clinical trial program in Canada. Shayne and Dr Sola assemble a team of passionate professionals to actualize the vision.

Toronto Stock Exchange

With the backing of hundreds of investors across North America and Europe, Universal Ibogaine completes a public listing on the TSX Venture Exchange to finance its Clinical Trial Application and the acquisition of its first treatment clinic in Canada.

Research & Development

Worldwide Anecdotal Data Suggests there are many benefits associated with Ibogaine Medical Treatments.

Ibogaine is a powerful medicine that requires administration in a clinical environment according to a rigorous safety protocol.

Ibogaine has demonstrated anti-addictive properties. 

An individual does not need to continue taking ibogaine on a regular basis and is not subjected to replace one highly addictive drug with another equally or more addictive.

Ibogaine medicalization may eliminate the use of addictive drug substitution treatments.

We are creating the gold standard in addiction treatment applying state of the art treatments in a holistic long term disease management model.

We are creating a network of clinics and after care programming to administer our treatments and provide ongoing care as required.

Opioid Detoxification

In a study published in 2018, New Zealand-based researchers assessed the effects of a single ibogaine treatment on 14 patients addicted to opioids and found that even 1 year later, opioid use and cravings were significantly reduced.

Microbial Properties of Ibogaine

Antimicrobial Properties

Studies in mice showed that iboga alkaloids reduced the number of deaths caused by Candida albicans infections. Due to its unique properties and composition, ibogaine inhibits the activity of enzymes called lipases. When combined with a commonly used antibiotic, it suppressed fungus development.

Natural Medicine

Appetite Suppressor

Synthetic iboga alkaloids have been proposed as a treatment for obesity in rats, based on a study from Albany Medical College. Chronic administration of the substance prevented increases in body weight, decreased fat deposition, and reduced sugar consumption.

Potential Antioxidant

In 2015, Serbian researchers found that ibogaine increases the activity of antioxidant enzymes in human red blood cells.

Mental State Stimulation

In observational trials, ibogaine improved symptoms of depression, anxiety, and obsessive-compulsive disorder for an extended period of time after the initial ibogaine treatment.

Anti-Cancer Properties

Early pre-clinical research has showed ibogaine’s ability to reverse multi-drug resistance in human cancer cells.

Ibogaine Faq

Frequently asked questions: answered

Ibogaine is a neuroactive compound which can be derived from various plants. Ibogaine has been shown to have a profound effect on the human brain. When administered in a clinical setting by trained facilitators and given the proper dosage, mindset and setting, ibogaine has demonstrated an ability to reset the brain and nervous system to pre addicted states. It repairs damaged brain tissues and its effects last long enough for a patient to recover and rebuild. Please contact us to learn more.

The so-called “mechanism of action” of ibogaine (how it works) is still not fully understood. However, we do know that it targets multiple receptor sites in the brain, including the opioid receptors, the NMDA glutamate receptor, the nicotinic receptors and so on. In addition, ibogaine stimulates the production of growth factor (GDNF specifically) which supports neuro-generative processes and the production of new dopamine cells. In addition, ibogaine metabolizes into noribogaine, which is a long-acting compound which effectively functions as an internal microdosing system for up to 3-4 months after being consumed.

Ibogaine is a profoundly powerful substance which has the power to completely change a patient’s life. For this reason it is crucial to experience an ibogaine treatment in a safe clinical setting with trained facilitators. 

Universal Ibogaine will soon be conducting Clinical Trials in Canada.

Ibogaine is primarily used in treating addiction for opiates and other highly-addictive drugs, though it is also becoming more common as a tool for personal and spiritual development. Recreational use of ibogaine is not recommended.

Ibogaine is a naturally occurring psychoactive indole alkaloid found in plants in the Apocynaceae family such as Tabernanthe iboga, Voacanga africana and Tabernaemontana undulata. In the iboga plant (Tabernanthe iboga), the highest concentration of ibogaine is found in the root bark. Lower concentrations of ibogaine are found in the rest of the plant along with other indole alkaloids in the same family.

Iboga is the ground root bark from the shrub Tabernanthe iboga, and contains over ten different alkaloids working in harmony with each other (the so-called “entourage effect”).

Ibogaine is a single molecule. People often report different experiences between the two. Because it is closer to a natural product, iboga requires consumption of more powder, whereas ibogaine is most often taken in small capsule form.

We do not fully understand yet the benefits and risks of Ibogaine, more conclusive studies are required to answer this.  However, at Universal Ibogaine it is our mission to progress research and develop effective treatments for addiction.

Ibogaine Science

The science behind the Ibogaine Cure for Addiction and Mental Health Trauma


Ibogaine seems to influence drug withdrawal in two primary ways:

Dopamine Regulations

Dopamine Regulation

Helps regulate levels of dopamine and serotonin in the brain, both of which are chemicals associated with pleasure and feelings of well-being. With its unique properties and chemical composition, ibogaine has the ability to block and guard dopamine receptors from harmful drugs such as opioids.

Restores Damage

Restores Damange

Second, ibogaine appears to help restore damaged areas of brain circuitry caused by long-term drug use. It offers one of the top solutions for opioid addiction available.

Addiction Symptom
Relief of Withdrawal 99%
Dopamine Regulation
regulate and optimized 95%
Seratonin Regulation
levels restored naturally 97%
Damage Restored
Circuitry 86%

Ibogaine regulates dopamine re-uptake and many other neurotransmitter systems.

Ibogaine metabolizes into Noribogaine, a serotonin re-uptake inhibitor that remains in the body for 1-4 months, eliminating addictive cravings

Universal Ibogaine is on the Path to Medicalize Ibogaine 

Clinical Trial applications are in D


Phase One

Phase Two

Phase Three

Universal Ibgoaine
Progress 40%



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